Aptima mRNA HPV Test
How does cervical cancer develop?
Cervical cancer develops as a result of long-term infection of the Human
Papilloma Virus (HPV). HPV infection is particularly common as most women of reproductive age
potentially become infected at some point in their lives. In most cases, the virus recedes on its own,
without leaving any damage to the cervix. However, there are few cases in which the virus persists and causes the so-called precancerous lesions, which are divided into low -grade (LGSIL-CIN1) and high-grade (HGSIL-CIN2-3).
The advantages of Aptima Test
A necessary and sufficient condition for the immortalization of cells, neoplastic alteration, and the development of cervical cancer is the expression of E6/E7 oncogenes. The diagnostic test that detects the mRNA expression of these 2; E6/E7 oncogenes, is the Aptima mRNA HPV test. The Aptima Test detects the expression of high-risk mRNA -carcinogenic types of the HPV virus. Therefore, it detects those HPV infections that are more likely to develop into severe damage. While other HPV tests target the virus’s DNA, the Aptima HPV test detects mRNA and therefore the active HPV infection. In other words, it detects the mechanisms that promote cell mutation and the possibility of developing cancer, while genotyping HPV virus. A negative Aptima mRNA HPV test does not rule out the presence of other subtypes of the virus, but they are expected to belong to the low-risk group for malignant cell proliferation and cancer. Aptima mRNA HPV detects 14 high-risk types, 3 of which (16, 18, & 45) are associated with 80% of all invasive cervical cancers, while 9 of them (16, 18, 45, 31, 31, 33, 52, 58, 35 & 39 ) are associated with > 85% of cervical cancers.
Frequently Asked Questions (FAQ)
The APTIMA mRNA HPV test detects the expression of high-risk mRNA -carcinogenic types of the HPV virus. Therefore, it detects those HPV infections that are more likely to develop into severe damage. While other HPV tests target the virus’s DNA, the Aptima HPV test detects mRNA and therefore the active HPV infection. Genotyping of all High-Risk HPV subtypes of interest is also fully performed.
The detection is performed by molecular analysis using real-time PCR in Vagina-cervical smear – Liquid Based Test Pap with the most reliable ThinPrep technique
The procedure of collecting the sample is simple and is performed during your visit to your gynecologist. Upon notification, microDiagnostics Ltd takes the sample and guarantees fast and reliable analysis
by bank card, bank deposit or online interbank deposit
One of the primary concerns of microDiagnostics’ Ltd is the protection of your personal data as well as the strict adherence to the conditions protecting your genetic material and medical results.
In full compliance with the General Data Protection Regulation (GDPR) we ensure that you are aware and conscious for any examination will be conducted and we do not announce results via phone calls.